This Grant Opportunity for Academic Liaison with Industry (GOALI) Designing Materials to Revolutionize and Engineer our Future (DMREF) project will develop new knowledge and strategies for creating metallic materials for ultra-high temperature applications. These applications are critical for improving the efficiency of jet engines in aerospace and turbines for land-based power plants, and will also lead to reduction of harmful carbon emissions. The new materials to be created and studied are based on the concept that metals can be reinforced by uniformly distributing a small amount of ceramic oxide phases throughout the metallic matrix. The presence of the oxide reinforcements can provide significant enhancement in strength and help protect the material against attack under harsh, high temperature environments. A new way to create these oxide-dispersion-strengthened (ODS) metal alloys will be pursued, using an approach pioneered by our collaborators at NASA Glenn Research Center (GRC). In this “additive manufacturing” approach, a moving laser melts and solidifies the metal and oxide powder, building up the material layer-by-layer. The project will further improve these materials by using additional strategies for strengthening the metals. New knowledge about the interaction between this new processing strategy, the resultant internal structure of the alloy, and mechanical behavior of these new materials will be generated in the project, and this knowledge will be made accessible using a new artificial-intelligence framework. This framework will enable the team to the optimize these additive ODS alloys for design objectives of interest to our partners at GE Aerospace and the Air Force Research Laboratory. The DMREF team includes 3 women and 1 black faculty member and will offer multiple opportunities for student research experiences targeting under-represented groups and veterans.