Applying the concept of topology to solid state systems has revolutionized our understanding of quantum phenomena and materials, and inspired the design of new functionalities in electronic, atomic, photonic, mechanical, and acoustic systems. For instance, topological insulators (TIs) are a class of materials that are electrically insulating in the bulk but host conductive surface states that are immune to impurities. These states enable near-perfect devices from imperfect interfaces, which are important for both conventional and quantum information technology. However, there exist a number of critical challenges in current TI materials that must be addressed before realizing their full potential. This project aims at overcoming these challenges by focusing on and further developing a new class of materials, quasi-one-dimensional (quasi-1D) TIs for novel electronic, optoelectronic and sensing functionalities, via an iterative loop of theoretical modeling and prediction, material synthesis, characterization and device prototyping. Successful implementation of the program will advance knowledge and technology on topological materials and ultimately pave the way for transforming next-generation information technology and sustainable energy solutions. Major educational activities will be integrated into the research activities by increasing participation of under-represented groups, mentoring undergraduate and graduate students in STEM disciplines, performing public outreach by team-visiting local public schools and leveraging the team’s Youtube channel and twitter, organizing virtual workshops, creating a new online course, providing a new face to physics and materials science with two women in leadership positions in this team, and providing open access to research and education outputs to the technical community and general public.